Asp 102 is designed for use in waterborne, semigloss coatings, and for highshear rubber compounding systems typical applications. In case of contact, immediately wash skin with soap and copious amounts of water. Accelon is a breakthrough omega3 technology that significantly accelerates omega3 absorption, so you get more omega3 to where its needed. Kollidon va 64 was procured from basf germany, soya lecithin was from vwr international ltd poole, england, avicel ph101 was from sigmaaldrich saint louis, usa, gelucire 50.
Basfs mining solutions business offers a diverse range of mineral processing and hydrometallurgical chemistries and technologies to improve process efficiencies and aid the. A meltable binder is used to agglomerate drug and other ingredients to reduce recrystallization potential through separation. They are linear nonionic polymers that are soluble in water. You can find detailed information on our product range by looking up your industry or using our product finder. Kollidon va 64 is an excellent binders for tablets and granules. Kollidon va 64 dan va 64 fine free download as pdf file. Chemicals are produced in a broad range of rigid twocomponent. Electronic printouts are current on the date printed. Basf offers all functional excipients to successfully develop a dc process for your drug, including key elements like appropriate binder and lubricant. Basf has been committed to the pharmaceutical industry since we introduced our original kollidon in the early 20th century. Department of pharmacy,jodhpur national university, narnadi,jhanwar road, jodhpur342001 2. An important property of kollidon va 64 in this application is its plasticity, which distinguishes it from povidone e.
The kollidon cl family is the industrys widest portfolio of superdisintegrants and dissolution enhancers. Formulation and evaluation of kollidon sr for phindependent. It gives much better results than any of the povidone grades or other drybinders of the group of cellulose derivatives. Between granules 2% and 5%, as a proportion of the final weight of the preparation, is usually used. Alamine 336 alamine 336 is a water insoluble, trioctyldecyl amine which is capable of forming oil soluble salts of anionic species at low ph. Development of amorphous dispersions of artemether with. Kollidon can be combined with all the usual filmforming agents such as polyvinyl acetate, cellulose derivatives or methacrylates. The drug master file guidance states the submission of a dmf is not required by law or fda. Safety data sheet this controlled document is confidential and contains proprietary information. Kollidon va 64 fine has been found to be an excellent dry binder for direct compression. An important property of kollidon va 64 in this application is the plasticity, which distinguishes the products from povidone e. Meltquenched solid dispersions mqsds of ba were prepared at. Coating suspension with kollidon 30 for manual sugar coating. Waterborne semigloss coatings, mechanical rubber goods, tpe tpo.
Basf supplies kollidon cl, kollidon clf and kollidon clsf as disintegrants for the pharmaceutical industry. Kollidon va 64 is a vinylpyrrolidonevinyl acetate copolymer that is soluble. Technical information kollidon va 64 939 march 2000. We have several search tools, listed above, that give you more efficient. Polyvinylpyrrolidone for the pharmaceutical industry basf no. Kollidon 30 is used as poreforming agents in film coatings. Germany, polyethylene caprolactampolyvinyl acetatepolyethylene glycol graft.
It is used as a dry binder in tabletting, as a granulating auxiliary and as a filmforming agent in the pharmaceutical industry. Sds formerly msds downloads for basf comfort foam, spraytite, enertite, walltite, spraytite, elastospray and elastotite g 20140 available here. Runoff of pharmaceuticals and personal care products 2 following application of biosolids to an agricultural field. Autofroth specially formulated foam chemical systems take full advantage of the pressurized dispensing equipments capabilities. Pvp k30 forms hard glossy transparent films and have adhesive, cohesive and dispersive properties. The product for the dctechnology is kollidon sr kollidon sr. Basf corporation 100 campus drive florham park, nj 07932, usa chemtrec.
Identification product identifier used on the label engenia recommended use of the chemical and restriction on use recommended use. A drug master file dmf is a submission of information to the u. The terms of this safety data sheet sds do not create or infer any warranty, express or implied, including by incorporation into or reference in the sellers sales agreement. If swallowed, wash out mouth with water provided person. Study the material safety data sheets for the hazards of the chemical, learn the instructions on handling, storage and the emergency measures in case of accident take our free online. Basf corporation 100 park avenue florham park, nj 07932, usa. Formulation and evaluation of kollidon sr for phindependent extended release matrix systems for propranolol hydrochloride haresh t mulani1, bhumin patel2, nehal j shah2 1. Molecular interaction studies of amorphous solid dispersions of the. No significant reaction of the human body to the product known. Identification product identifier used on the label engenia. This page has links to all data sheets in matweb for the manufacturer basf. Product and company identification company 24 hour.
They also improve the water solubility of the coating. Quarterly statement pdf annual shareholders meeting 2020. Methods employed to yield solid dispersions or solid solutions of nces include coevaporates, ground dispersions, or hot melt extrudates of nces with hydrophilic matrix carriers. With innovative products, global field support and industry leading technical expertise, basf mining solutions provides sustainable solutions which increase productivity, recovery and flexibility throughout the mining operations including leaching, solvent extraction, flotation, solidliquid separation and tailings management. Jun 12, 2014 methods employed to yield solid dispersions or solid solutions of nces include coevaporates, ground dispersions, or hot melt extrudates of nces with hydrophilic matrix carriers like high molecular weight polyethyleneglycols, polyvinyl alcohols, hydroxypropyl cellulose, polyethylene oxide, eudragit e 100, soluplus, and kollidon va 64 that. Msds shows how the material reacts to environment and how to store it properly. Due to its particle size kollidon cl corresponds to type a in. Safety data sheet kollidon northwest missouri state. Kollidon must be stored tightly closed and protected from light at max. The terms of this safety data sheet sds do not create or infer any warranty, express or implied, including by incorporation into or reference in the sellers. We have several search tools, listed above, that give you more efficient methods to reach the information that you need. Between 2% and 8%, as a proportion of the final weight of the preparation, is usually used. Mechanism and improved dissolution of glycyrrhetinic acid. Technical information kollidon va 64 939 march 2000 mpm.
Msds includes information such as melting point, boiling point, and flash point of a hazardous material. Runoff of pharmaceuticals and personal care products 2 following application of. Describes the effects when workers come into contact with the chemical and how to proceed in case of an accident. Separate technical data sheets are available for the insoluble kollidon grades crospovidone and for kollidon va 64, a copolymer of nvinylpyrrolidone and vinyl acetate copovidone. If kollidon 90 f is kept refrigerated, its k value decreases more slowly.
Product and company identification company 24 hour emergency response information basf corporation 100 campus drive florham park, nj 07932, usa chemtrec. Nevertheless, kollidon va 64 usually still absorbs too much water, so that it can seldom be used as the sole filmforming agent in a formulation. Soluplus, kollidon va64, and kollidon k90 were donated by basf usa. Details of the supplier of the safety data sheet company. Helping make products better safety data sheet kollidon va 64 fine revision date. We combine economic success with environmental protection and social responsibility. Preparation and characterization of rilpivirine solid. Alcoholic pigment suspensions can be prepared with a mixture of shellac and soluble kollidon, and these give homogeneous coatings. Today we solve unmet formulation needs and offer intelligent solutions for today and tomorrows challenges in drug formulation.
Kollidon va 64 was procured from basf germany, soya lecithin was from vwr international ltd poole, england, avicel ph101 was from sigmaaldrich saint louis, usa, gelucire 50 was provided by gattefosse cedex, france, ethanol absolute 99. It is therefore recommended to combine it with less hygroscopic substances such as. In addition, they improve bioavailability of certain poorly soluble apis. Pvp k30 polymer pvp k30 polymer description pvp polyvinylpyrrolidone k30 polymer is a hygroscopic, amorphous polymer. Product and company identification company 24 hour emergency response information basf corporation 100 park avenue florham park, nj 07932, usa chemtrec. Product properties kollidon sr is derived from a polyvinyl acetatedispersion kollicoat sr 30d and. Kollidon clm is usually used as a suspension stabilizer. Sigmaaldrich is a leading life science and high technology company whose biochemical, organic chemical products, kits and services are used in scientific research. Kollidon va 64 is a vinylpyrrolidonevinyl acetate copolymer that is soluble both in water and in alcohol. The hardness, friability, porosity and disintegration time of lactose and starch placebo tablets produced with kollidon va 64 fine is directly related to the compression force.
Due to its particle size kollidon cl corresponds to type a in ph. By using our services, you agree to our use of cookies. Indication of any immediate medical attention and special treatment needed note to physician. They are linear nonionic polymers that are soluble in water and organic solvents and are ph stable. Quality standard kollidon cl meets the requirements of the current monographs for crospovidone in ph. Soluplus and kollidon va 64, were gifted from basf ag germany. Kollidon va 64 dan va 64 fine tablet pharmacy magnesium. Arm sds with the different hydrophilic polymers were obtained by spray drying water. Safety data sheet plateau msds catalog service llc. Safety data sheet luran s 778 t natural revision date. These highly functional crosslinked pvp polymers ensure that active ingredients are released from any solid dosage form at exceptionally high speed. Description kollidon cl is manufactured by a polymerisation process that yields mainly physically crosslinked insoluble polyvinylpyrrolidone in the.
Elastopor h is a closedcell polyurethane rigid foam used for many applications in the field of heat and cold protection due to its excellent insulation properties. Through science and innovation we provide our customers with products to meet the current and future needs of business and society. Technical information soluble kollidon january 2004. Since then we have continuously expanded our solution offer. Solid dispersions of arm were prepared with soluplus, kollidon va 64, hpmc and eudragit epo at weight ratios of. Sodium stearyl fumarate is a fine, white powder with a flat and round shaped particles with agglomerates. The submission of a dmf is not required by law or fda regulation. Safety data sheet northwest missouri state university. Basf corporation 100 campus drive florham park, nj 07932. Both polyvinylpyrrolidone k30, kollidon 30 average mw 40,000 and vinylpyrrolidonevinyl acetate copolymer kollidon va 64 were generous gifts from basf distributed via elite organic sdn. Alamine 336 finds use as an agent for producing oil soluble salts of various anions or as a reagent in recovering andor purifying organic or inorganic species which are capable of. This madetomeasure insulant boasts extremely low thermal conductivity levels matched by no other conventional insulant.
These highly functional crosslinked pvp polymers ensure that active ingredients. Kollidon va 64 forms films that are soluble at all ph values. You can find detailed information on our product range. They are less hygroscopic and more elastic than those formed by povidone e. Dharmaj degree pharmacy college, dharmaj388430 abstract. The characterization and dissolution performances of spray dried. At basf, we create chemistry for a sustainable future. Sodium stearyl fumarate is used as a lubricant for the production of solid. Safety data sheet kollidon va 64 fine revision date. The comparison between dissolution profiles of pms and sds systems.
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