Sodium stearyl fumarate is used as a lubricant for the production of solid. Electronic printouts are current on the date printed. They are linear nonionic polymers that are soluble in water. Safety data sheet kollidon va 64 fine revision date. Today we solve unmet formulation needs and offer intelligent solutions for today and tomorrows challenges in drug formulation. Between granules 2% and 5%, as a proportion of the final weight of the preparation, is usually used. They also improve the water solubility of the coating. Both polyvinylpyrrolidone k30, kollidon 30 average mw 40,000 and vinylpyrrolidonevinyl acetate copolymer kollidon va 64 were generous gifts from basf distributed via elite organic sdn. Kollidon va 64 is a vinylpyrrolidonevinyl acetate copolymer that is soluble. Kollidon va 64 fine has been found to be an excellent dry binder for direct compression. Methods employed to yield solid dispersions or solid solutions of nces include coevaporates, ground dispersions, or hot melt extrudates of nces with hydrophilic matrix carriers. Through science and innovation we provide our customers with products to meet the current and future needs of business and society.
One of the many products to emerge from this work was soluble polyvinylpyrrolidone. Safety data sheet plateau msds catalog service llc. Accelon is a breakthrough omega3 technology that significantly accelerates omega3 absorption, so you get more omega3 to where its needed. Description kollidon cl is manufactured by a polymerisation process that yields mainly physically crosslinked insoluble polyvinylpyrrolidone in the. No significant reaction of the human body to the product known. We have several search tools, listed above, that give you more efficient.
The terms of this safety data sheet sds do not create or infer any warranty, express or implied, including by incorporation into or reference in the sellers sales agreement. Product and company identification company 24 hour emergency response information basf corporation 100 campus drive florham park, nj 07932, usa chemtrec. It gives much better results than any of the povidone grades or other drybinders of the group of cellulose derivatives. Kollidon va 64 forms films that are soluble at all ph values. Soluplus and kollidon va 64, were gifted from basf ag germany. Basf has been committed to the pharmaceutical industry since we introduced our original kollidon in the early 20th century. Nevertheless, kollidon va 64 usually still absorbs too much water, so that it can seldom be used as the sole filmforming agent in a formulation. Solid dispersions of arm were prepared with soluplus, kollidon va 64, hpmc and eudragit epo at weight ratios of. Kollidon va 64 is a vinylpyrrolidonevinyl acetate copolymer that is soluble both in water and in alcohol. Separate technical data sheets are available for the insoluble kollidon grades crospovidone and for kollidon va 64, a copolymer of nvinylpyrrolidone and vinyl acetate copovidone. Technical information soluble kollidon january 2004. Due to its particle size kollidon cl corresponds to type a in ph. Safety data sheet kollidon northwest missouri state. Product and company identification company 24 hour emergency response information basf corporation 100 park avenue florham park, nj 07932, usa chemtrec.
This madetomeasure insulant boasts extremely low thermal conductivity levels matched by no other conventional insulant. Msds includes information such as melting point, boiling point, and flash point of a hazardous material. Technical information kollidon va 64 939 march 2000. Safety data sheet northwest missouri state university. Safety data sheet this controlled document is confidential and contains proprietary information. Details of the supplier of the safety data sheet company. Identification product identifier used on the label engenia recommended use of the chemical and restriction on use recommended use. Quality standard kollidon cl meets the requirements of the current monographs for crospovidone in ph. Basfs mining solutions business offers a diverse range of mineral processing and hydrometallurgical chemistries and technologies to improve process efficiencies and aid the. Formulation and evaluation of kollidon sr for phindependent extended release matrix systems for propranolol hydrochloride haresh t mulani1, bhumin patel2, nehal j shah2 1. You can find detailed information on our product range. By using our services, you agree to our use of cookies. Molecular interaction studies of amorphous solid dispersions of the.
Runoff of pharmaceuticals and personal care products 2 following application of biosolids to an agricultural field. Runoff of pharmaceuticals and personal care products 2 following application of. Describes the effects when workers come into contact with the chemical and how to proceed in case of an accident. These highly functional crosslinked pvp polymers ensure that active ingredients. Basf offers all functional excipients to successfully develop a dc process for your drug, including key elements like appropriate binder and lubricant. Identification product identifier used on the label engenia. It is used as a dry binder in tabletting, as a granulating auxiliary and as a filmforming agent in the pharmaceutical industry. They are less hygroscopic and more elastic than those formed by povidone e. Asp 102 is designed for use in waterborne, semigloss coatings, and for highshear rubber compounding systems typical applications. The terms of this safety data sheet sds do not create or infer any warranty, express or implied, including by incorporation into or reference in the sellers. Mechanism and improved dissolution of glycyrrhetinic acid. Basf corporation 100 campus drive florham park, nj 07932.
Soluplus, kollidon va64, and kollidon k90 were donated by basf usa. We have several search tools, listed above, that give you more efficient methods to reach the information that you need. Indication of any immediate medical attention and special treatment needed note to physician. Between 2% and 8%, as a proportion of the final weight of the preparation, is usually used. Msds shows how the material reacts to environment and how to store it properly. Germany, polyethylene caprolactampolyvinyl acetatepolyethylene glycol graft. A drug master file dmf is a submission of information to the u. The submission of a dmf is not required by law or fda regulation. Formulation and evaluation of kollidon sr for phindependent. Pvp k30 polymer pvp k30 polymer description pvp polyvinylpyrrolidone k30 polymer is a hygroscopic, amorphous polymer. If swallowed, wash out mouth with water provided person.
Arm sds with the different hydrophilic polymers were obtained by spray drying water. Waterborne semigloss coatings, mechanical rubber goods, tpe tpo. At basf, we create chemistry for a sustainable future. Alamine 336 finds use as an agent for producing oil soluble salts of various anions or as a reagent in recovering andor purifying organic or inorganic species which are capable of. Basf corporation 100 park avenue florham park, nj 07932, usa. Basf corporation 100 campus drive florham park, nj 07932, usa chemtrec. Basf supplies kollidon cl, kollidon clf and kollidon clsf as disintegrants for the pharmaceutical industry. Dharmaj degree pharmacy college, dharmaj388430 abstract. A meltable binder is used to agglomerate drug and other ingredients to reduce recrystallization potential through separation. Kollidon va 64 is an excellent binders for tablets and granules.
In addition, they improve bioavailability of certain poorly soluble apis. It is therefore recommended to combine it with less hygroscopic substances such as. They are linear nonionic polymers that are soluble in water and organic solvents and are ph stable. Product and company identification company 24 hour. The product for the dctechnology is kollidon sr kollidon sr. Due to its particle size kollidon cl corresponds to type a in. An important property of kollidon va 64 in this application is the plasticity, which distinguishes the products from povidone e. Helping make products better safety data sheet kollidon va 64 fine revision date. In case of contact, immediately wash skin with soap and copious amounts of water. Preparation and characterization of rilpivirine solid. You can find detailed information on our product range by looking up your industry or using our product finder. These highly functional crosslinked pvp polymers ensure that active ingredients are released from any solid dosage form at exceptionally high speed. Elastopor h is a closedcell polyurethane rigid foam used for many applications in the field of heat and cold protection due to its excellent insulation properties.
Coating suspension with kollidon 30 for manual sugar coating. This page has links to all data sheets in matweb for the manufacturer basf. Kollidon va 64 was procured from basf germany, soya lecithin was from vwr international ltd poole, england, avicel ph101 was from sigmaaldrich saint louis, usa, gelucire 50. Sigmaaldrich is a leading life science and high technology company whose biochemical, organic chemical products, kits and services are used in scientific research. Development of amorphous dispersions of artemether with. Alamine 336 alamine 336 is a water insoluble, trioctyldecyl amine which is capable of forming oil soluble salts of anionic species at low ph. Sds formerly msds downloads for basf comfort foam, spraytite, enertite, walltite, spraytite, elastospray and elastotite g 20140 available here. If kollidon 90 f is kept refrigerated, its k value decreases more slowly. Sodium stearyl fumarate is a fine, white powder with a flat and round shaped particles with agglomerates. Polyvinylpyrrolidone for the pharmaceutical industry basf no. With innovative products, global field support and industry leading technical expertise, basf mining solutions provides sustainable solutions which increase productivity, recovery and flexibility throughout the mining operations including leaching, solvent extraction, flotation, solidliquid separation and tailings management. Technical information kollidon va 64 939 march 2000 mpm. Alcoholic pigment suspensions can be prepared with a mixture of shellac and soluble kollidon, and these give homogeneous coatings.
Autofroth specially formulated foam chemical systems take full advantage of the pressurized dispensing equipments capabilities. Quarterly statement pdf annual shareholders meeting 2020. Chemicals are produced in a broad range of rigid twocomponent. Meltquenched solid dispersions mqsds of ba were prepared at. Kollidon va 64 dan va 64 fine free download as pdf file. Pvp k30 forms hard glossy transparent films and have adhesive, cohesive and dispersive properties. The kollidon cl family is the industrys widest portfolio of superdisintegrants and dissolution enhancers. The comparison between dissolution profiles of pms and sds systems. We combine economic success with environmental protection and social responsibility.
Jun 12, 2014 methods employed to yield solid dispersions or solid solutions of nces include coevaporates, ground dispersions, or hot melt extrudates of nces with hydrophilic matrix carriers like high molecular weight polyethyleneglycols, polyvinyl alcohols, hydroxypropyl cellulose, polyethylene oxide, eudragit e 100, soluplus, and kollidon va 64 that. Product properties kollidon sr is derived from a polyvinyl acetatedispersion kollicoat sr 30d and. Study the material safety data sheets for the hazards of the chemical, learn the instructions on handling, storage and the emergency measures in case of accident take our free online. Since then we have continuously expanded our solution offer. Kollidon va 64 was procured from basf germany, soya lecithin was from vwr international ltd poole, england, avicel ph101 was from sigmaaldrich saint louis, usa, gelucire 50 was provided by gattefosse cedex, france, ethanol absolute 99.
Kollidon clm is usually used as a suspension stabilizer. Kollidon 30 is used as poreforming agents in film coatings. Safety data sheet luran s 778 t natural revision date. Kollidon va 64 dan va 64 fine tablet pharmacy magnesium. The drug master file guidance states the submission of a dmf is not required by law or fda. Kollidon can be combined with all the usual filmforming agents such as polyvinyl acetate, cellulose derivatives or methacrylates. An important property of kollidon va 64 in this application is its plasticity, which distinguishes it from povidone e. The hardness, friability, porosity and disintegration time of lactose and starch placebo tablets produced with kollidon va 64 fine is directly related to the compression force. Kollidon must be stored tightly closed and protected from light at max.
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